{"id":109945,"date":"2025-10-07T16:00:55","date_gmt":"2025-10-07T20:00:55","guid":{"rendered":"https:\/\/www.sharpfootballanalysis.com\/?p=109945"},"modified":"2025-10-07T16:36:20","modified_gmt":"2025-10-07T20:36:20","slug":"best-nfl-futures-bets-picks-2025","status":"publish","type":"post","link":"https:\/\/www.sharpfootballanalysis.com\/betting\/best-nfl-futures-bets-picks-2025\/","title":{"rendered":"2025 NFL Futures: Best Bets, Odds & Predictions"},"content":{"rendered":"

The NFL futures markets do not disappear once the season kicks off.<\/p>\n

Super Bowl odds, award odds, and many other futures bets will remain available throughout the NFL season.<\/p>\n

Every week, we will look at the top options and best values in those markets.<\/p>\n

Don't Miss Out on the Best Betting Recommendations Available<\/strong><\/p>\n

Warren Sharp is entering his 20th year providing winning betting recommendations to clients.
\n<\/em><\/p>\n

A $100 bettor has won\u00a0$3,586<\/strong>\u00a0following Warren\u2019s picks so far this season.<\/em><\/p>\n

A $100 bettor won\u00a0$15,636<\/strong>\u00a0following Warren\u2019s picks last season.<\/em><\/p>\n

Click here to learn more about 2025 Betting Packages!<\/strong><\/a><\/em><\/p>\n

2025 NFL Futures Betting Recommendation: San Francisco 49ers to be NFC\u2019s No. 1 Seed (+470)<\/h2>\n

I\u2019m going back to the well with a suggestion for betting on the NFC\u2019s No. 1 seed.<\/p>\n

I previously suggested the Packers before their loss to the Browns and tie with the Cowboys.<\/p>\n

So…I\u2019m hoping for a better runout after this suggestion.<\/p>\n

San Francisco\u2019s +470 odds to be the NFC\u2019s No. 1 seed at FanDuel are a relative bargain versus +375 at Caesars, +400 at DraftKings, and +450 at Fanatics.<\/p>\n

Again, odds shopping is critical for all wagers, and this is the latest example.<\/p>\n

Find the best odds using the OddsJam Screen. Simply click here to try OddsJam for\u00a0FREE\u00a0for two weeks!<\/strong><\/em><\/a><\/p>\n

The 49ers don\u2019t have the most eye-catching numbers.<\/p>\n

According to Sumer Sports, the 49ers are 17th in Expected Points Added (EPA) per play (0.02), seventh in success rate (47.99%), tied for 10th in EPA allowed per play (-0.03), and 23rd in success rate (45.78%) allowed.<\/p>\n

Additionally, their +8 point differential is actually the second-worst in the NFC West, only one point better than Arizona\u2019s +7 point differential.<\/p>\n

Nevertheless, the context moves San Francisco\u2019s overall numbers from somewhat palatable to somewhat impressive.<\/p>\n

First, their only loss was a home game against the now 4-1 Jaguars with Brock<\/strong> Purdy<\/strong> struggling as the starter after rushing back from his toe injury.<\/p>\n

Second, they\u2019ve defeated all three of their NFC West opponents, including road victories against the Seahawks in Week 1 and against the Rams in Week 5.<\/p>\n

The 49ers have raced out to a 4-1 record despite navigating multiple injuries and possibly playing the toughest stretch of their schedule.<\/p>\n

Three of San Francisco\u2019s five opponents have a winning record this season, and four have a positive point differential.<\/p>\n

The 49ers will face only three more teams with a winning record, and two with a .500 record.<\/p>\n

Furthermore, just six of San Francisco\u2019s remaining opponents have a positive point differential.<\/p>\n

The locations and times for San Francisco\u2019s remaining games are favorable, too.<\/p>\n

The 49ers are in Tampa Bay this week and in Indianapolis in Week 16, but they\u2019ll host the Seahawks in Week 18, host the Falcons in Week 7, and host the Bears in Week 17.<\/p>\n

So, three of their five remaining games against teams with at least a .500 record will be in San Francisco.<\/p>\n

The 49ers will only have the misfortune of playing three games in the 1:00 p.m. ET window, barring what time their Week 18 home game against the Seahawks ends up being.<\/p>\n

Unfortunately, the banged-up 49ers won\u2019t have the services of stud EDGE Nick<\/strong> Bosa<\/strong> for the remainder of the season.<\/p>\n

They will get many reinforcements back, though.<\/p>\n

WRs Ricky<\/strong> Pearsall<\/strong> and Jauan Jennings<\/strong> were out last week and could return as soon as this week.<\/p>\n

Starting OG Ben<\/strong> Bartch<\/strong> will eventually return from a high-ankle sprain and an injured reserve stint, and TE George<\/strong> Kittle<\/strong> likely won\u2019t be back this week, but Week 7 is in the crosshairs.<\/p>\n

WR Brandon<\/strong> Aiyuk<\/strong> could also provide the offense with a spark, depending on how he plays in his return from ACL\/MCL surgery on his knee.<\/p>\n

The 49ers also opened the 21-day practice window for second-year S Malik Mustapha<\/strong>.<\/p>\n

Among 83 safeties who played at least 450 snaps last year, Mustapha was Pro Football Focus\u2019s (PFF) 45th-graded safety.<\/p>\n

His grade was approximately average, which wasn\u2019t too shabby for a rookie.<\/p>\n

PFF\u2019s player grades also aren\u2019t the be-all, end-all. Still, the second-year pro\u2019s return will add a thumper to San Francisco\u2019s secondary.<\/p>\n

And, of course, Mac Jones<\/strong>\u2019 quality play will allow the 49ers to give Purdy sufficient time to recover from his toe injury.<\/p>\n

Among 32 quarterbacks with at least 100 dropbacks this season, Jones is PFF\u2019s 13th-graded passer.<\/p>\n

Furthermore, among 32 quarterbacks with at least 100 plays this year, Jones is 12th in EPA per play (0.13).<\/p>\n

Purdy has tallied 0.16 EPA per play this year.<\/p>\n

Last year, he rattled off 0.18 EPA per play, and he had an NFL-high 0.29 EPA per play among quarterbacks with at least 50 plays in 2023.<\/p>\n

As well as Jones has played, Purdy will be an upgrade if his toe doesn\u2019t hamper his play after he reprises his starting role.<\/p>\n

The Lions, Packers, Eagles, and Buccaneers are San Francisco\u2019s fiercest competition for the NFC\u2019s No. 1 seed.<\/p>\n

However, their roads to the NFC\u2019s No. 1 seed are littered with more difficult matchups, making the 49ers\u2019 +470 odds to capture the NFC\u2019s No. 1 seed offered at FanDuel compelling.<\/p>\n

Previous Recommendations:<\/strong><\/p>\n